Thu27Sep20184:45 pmPreston Theatre
Colloquium Series: Ethanol & medicinesShow content
Dr. Lucija Peterlin Masic of the University of Ljubljana
Ethanol is one of the most widely used legal psychoactive substances with high potential for abuse. Interactions between ethanol and drugs may occur with the concurrent use of ethanol and medicinal products. The elderly frequently use ethanol and prescription drugs together; therefore the risk for side effects is higher. Concomitant use of ethanol and drugs may result in pharmacokinetic or pharmacodynamic interactions. Pharmacokinetic interactions occur when ethanol directly affects the normal metabolism of the drug and its concentration in the blood. Pharmacodynamic interactions are primarily the result of additive effects of ethanol and drugs on the central nervous system. Therefore, there is a risk of excessive sedation when using drugs that act depressive on the central nervous system. In reality, interactions between ethanol and drugs are often complex, as people may be exposed to more than two psychotropic substances at the same time. In the presentation, I will focus primarily on action of the ethanol on the organism and on providing a better insight into the mechanisms underlying the known pharmacokinetic and pharmacodynamic drug interactions with ethanol.